Publications

2026

  • 📄
    Morphological Programming in Gold (III) Coordination Assemblies via pH-Modulated Noncovalent Hierarchy
    Yelan Xiao, Xiang Zhou, Nuo Cheng, Jianxin Ma, Jiacheng Yang, Jiarong Tian, Guolei Gao, Zhen Zhang, Mu-Peng Luo, Shou-Guo Wang, 李思思, Tong Shu, Xueji Zhang
    *ACS Appl. Mater. Interfaces*

2025

  • 📄
    Single-cell transcriptomics reveals a compartmentalized antiviral interferon response in the nasal epithelium of mice
    Xuefei Wang, Meng Dong, Xinchao Wu, Daniel Schnepf, Julia Thiel, Wenfei Sun, Christian Wolfrum, 李思思, Wenfei Jin, Peter Staeheli
    *J. Virol.*

2023

  • 📄
    Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis
    Jun Yang, Reqing He, Zhipeng Qu, Jinbao Gu, Liyun Jiang, Xiangqiang Zhan, Ying Gao, David L Adelson, 李思思, Zhen-Yu Wang, Youlin Zhu, Dong Wang
    *Dev. Cell*
  • 📄
    Molecular basis of the plant ROS1-mediated active DNA demethylation
    Xuan Du, Zhenlin Yang, Guohui Xie, Changshi Wang, Laixing Zhang, Kaige Yan, Maojun Yang, 李思思, Jian-Kang Zhu, Jiamu Du
    *Nat. Plants*
  • 📄
    Structure and mechanism of the plant RNA polymerase V
    Guohui Xie, Xuan Du, Hongmiao Hu, 李思思, Xiaofeng Cao, Steven E Jacobsen, Jiamu Du
    *Science*

2022

  • 📄
    A SYBR gold-based label-free in vitro dicing assay
    Qian Wang, Yan Xue, Laixing Zhang, Zhenhui Zhong, Suhua Feng, Changshi Wang, Lifan Xiao, Zhenlin Yang, C Jake Harris, Zhe Wu, Jixian Zhai, Maojun Yang, Sisi Li, Steven E Jacobsen, Jiamu Du
    *Bio-protocol*
  • 📄
    Making a 6mA demethylase
    李思思, Jiamu Du
    *Nat. Chem. Biol.*
  • 📄
    Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production
    Xuan Du, Zhenlin Yang, Alfredo Jose Florez Ariza, Qian Wang, Guohui Xie, 李思思, Jiamu Du
    *Plant Cell*

2021

  • 📄
    Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex
    Xiawei Huang, Hongmiao Hu, Alexandre Webster, Fan Zou, Jiamu Du, Dinshaw J Patel, Ravi Sachidanandam, Katalin Fejes Toth, Alexei A Aravin, 李思思
    *Nat. Commun.*
  • 📄
    CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis
    Yifeng Hou, Jing Sun, Baixing Wu, Yangyang Gao, Hongbo Nie, Zhentian Nie, Shuxuan Quan, Yong Wang, Xiaofeng Cao, 李思思
    *Mol. Plant*
  • 📄
    Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation
    Qian Wang, Yan Xue, Laixing Zhang, Zhenhui Zhong, Suhua Feng, Changshi Wang, Lifan Xiao, Zhenlin Yang, C Jake Harris, Zhe Wu, Jixian Zhai, Maojun Yang, Sisi Li, Steven E Jacobsen, Jiamu Du
    *Science*
  • 📄
    Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release
    Wanqiu Li, Linlin Wang, Bradley M Wierbowski, Mo Lu, Feitong Dong, Wenchen Liu, 李思思, Peiyi Wang, Adrian Salic, Xin Gong
    *Nat. Commun.*
  • 📄
    Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex
    李思思, Tian Xie, Peng Liu, Lei Wang, Xin Gong
    *Nat. Struct. Mol. Biol.*
  • 📄
    TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis
    Hongmiao Hu, Shu Tian, Guohui Xie, Rui Liu, Nana Wang, 李思思, Yuehui He, Jiamu Du
    *PNAS*

2020

  • 📄
    Drosophila YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs
    Fan Zou, Renjun Tu, Bo Duan, Zhenlin Yang, Zhaohua Ping, Xiaoqing Song, Shiyuan Chen, Andrew Price, Hua Li, Allison Scott, Anoja Perera, Sisi Li, Ting Xie
    *PNAS*
  • 📄
    Dual recognition of H3K4me3 and DNA by the ISWI component ARID5 regulates the floral transition in Arabidopsis
    Lian-Mei Tan, Rui Liu, Bo-Wen Gu, Cui-Jun Zhang, Jinyan Luo, Jing Guo, Yuhua Wang, Lixian Chen, Xuan Du, 李思思
    *Plant Cell*

2019

  • 📄
    Structure of Arabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications for N6-methyl-AMP recognition and processing
    Baixing Wu, Dong Zhang, Hongbo Nie, Senlin Shen, Yan Li, 李思思
    *RNA Biol.*
  • 📄
    The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor
    Shuzhi Zheng, Hongmiao Hu, Huimin Ren, Zhenlin Yang, Qi Qiu, Weiwei Qi, Xinye Liu, Xiaomei Chen, Xiekui Cui, 李思思
    *Nat. Commun.*

2018

  • 📄
    Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation
    Xueqin Li, C Jake Harris, Zhenhui Zhong, Wei Chen, Rui Liu, Bei Jia, Zonghua Wang, 李思思, Steven E Jacobsen, Jiamu Du
    *PNAS*
  • 📄
    Structure of the Arabidopsis JMJ14-H3K4me3 complex provides insight into the substrate specificity of KDM5 subfamily histone demethylases
    Zhenlin Yang, Qi Qiu, Wei Chen, Bei Jia, Xiaomei Chen, Hongmiao Hu, Kaixuan He, Xian Deng, 李思思, W Andy Tao
    *Plant Cell*

2016

  • 📄
    Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors
    Yung-Chia Ariel Chen, Evelyn Stuwe, Yicheng Luo, Maria Ninova, Adrien Le Thomas, Ekaterina Rozhavskaya, 李思思, Sivani Vempati, John D Laver, Dinshaw J Patel
    *Mol. Cell*
  • 📄
    Drosha and Dicer: Slicers cut from the same cloth
    李思思, Dinshaw J Patel
    *Cell Res.*
  • 📄
    Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
    李思思, Linda Yen, William A Pastor, Jonathan B Johnston, Jiamu Du, Colin J Shew, Wanlu Liu, Jamie Ho, Bryan Stender, Amander T Clark, Alma L Burlingame, Lucia Daxinger, Dinshaw J Patel, Steven E Jacobsen
    *PNAS*
  • 📄
    Structural basis for the unique multivalent readout of unmodified H3 tail by Arabidopsis ORC1b BAH-PHD cassette
    李思思, Zhenlin Yang, Xuan Du, Rui Liu, Alex W Wilkinson, Or Gozani, Steven E Jacobsen, Dinshaw J Patel, Jiamu Du
    *Structure*
  • 📄
    Structure and function of the bacterial decapping enzyme NudC
    Katharina Höfer, 李思思, Florian Abele, Jens Frindert, Jasmin Schlotthauer, Julia Grawenhoff, Jiamu Du, Dinshaw J Patel, Andres Jäschke
    *Nat. Chem. Biol.*
  • 📄
    The effect of MicroRNA bantam on baculovirus AcMNPV infection in vitro and in vivo
    Xiaojie Shi, Zihan Ran, 李思思, Juan Yin, Jiang Zhong
    *Viruses*

2015

  • 📄
    Aub and Ago3 are recruited to nuage through two mechanisms to form a ping-pong complex assembled by Krimper
    Alexandre Webster, 李思思, Junho K Hur, Malte Wachsmuth, Justin S Bois, Edward M Perkins, Dinshaw J Patel, Alexei A Aravin
    *Mol. Cell*
  • 📄
    TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms
    Boseon Kim, Minju Ha, Luuk Loeff, Hyeshik Chang, Dhirendra K Simanshu, 李思思, Mohamed Fareh, Dinshaw J Patel, Chirlmin Joo, V Narry Kim
    *EMBO J.*

2014

  • 📄
    Mechanism of DNA methylation-directed histone methylation by KRYPTONITE
    Jiamu Du, Lianna M Johnson, Martin Groth, Suhua Feng, Christopher J Hale, 李思思, Ajay A Vashisht, Javier Gallego-Bartolome, James A Wohlschlegel, Dinshaw J Patel
    *Mol. Cell*
  • 📄
    Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
    Adrien Le Thomas, Evelyn Stuwe, 李思思, Jiamu Du, Georgi Marinov, Nikolay Rozhkov, Yung-Chia Ariel Chen, Yicheng Luo, Ravi Sachidanandam, Katalin Fejes Toth
    *Genes Dev.*

2013

  • 📄
    An example conference paper
    李思思, Robert Ford
    In *ICW*
  • 📄
    Functional and structural characterization of DNMT2 from Spodoptera frugiperda
    李思思, Jiamu Du, Hui Yang, Juan Yin, Jianping Ding, Jiang Zhong
    *J. Mol. Cell Biol.*
  • 📄
    Identification and characterization of the Spodoptera Su (var) 3-9 histone H3K9 trimethyltransferase and its effect in AcMNPV infection
    Binbin Li, 李思思, Juan Yin, Jiang Zhong
    *PLoS One*