Publications

2026

  • πŸ“„
    Morphological Programming in Gold (III) Coordination Assemblies via pH-Modulated Noncovalent Hierarchy
    Yelan Xiao, Xiang Zhou, Nuo Cheng, Jianxin Ma, Jiacheng Yang, Jiarong Tian, Guolei Gao, Zhen Zhang, Mu-Peng Luo, Shou-Guo Wang, Sisi Li, Tong Shu, Xueji Zhang
    *ACS Appl. Mater. Interfaces*

2025

  • πŸ“„
    Single-cell transcriptomics reveals a compartmentalized antiviral interferon response in the nasal epithelium of mice
    Xuefei Wang, Meng Dong, Xinchao Wu, Daniel Schnepf, Julia Thiel, Wenfei Sun, Christian Wolfrum, Sisi Li, Wenfei Jin, Peter Staeheli
    *J. Virol.*

2023

  • πŸ“„
    Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis
    Jun Yang, Reqing He, Zhipeng Qu, Jinbao Gu, Liyun Jiang, Xiangqiang Zhan, Ying Gao, David L Adelson, Sisi Li, Zhen-Yu Wang, Youlin Zhu, Dong Wang
    *Dev. Cell*
  • πŸ“„
    Molecular basis of the plant ROS1-mediated active DNA demethylation
    Xuan Du, Zhenlin Yang, Guohui Xie, Changshi Wang, Laixing Zhang, Kaige Yan, Maojun Yang, Sisi Li, Jian-Kang Zhu, Jiamu Du
    *Nat. Plants*
  • πŸ“„
    Structure and mechanism of the plant RNA polymerase V
    Guohui Xie, Xuan Du, Hongmiao Hu, Sisi Li, Xiaofeng Cao, Steven E Jacobsen, Jiamu Du
    *Science*

2022

  • πŸ“„
    A SYBR gold-based label-free in vitro dicing assay
    Qian Wang, Yan Xue, Laixing Zhang, Zhenhui Zhong, Suhua Feng, Changshi Wang, Lifan Xiao, Zhenlin Yang, C Jake Harris, Zhe Wu, Jixian Zhai, Maojun Yang, Sisi Li, Steven E Jacobsen, Jiamu Du
    *Bio-protocol*
  • πŸ“„
    Making a 6mA demethylase
    Sisi Li, Jiamu Du
    *Nat. Chem. Biol.*
  • πŸ“„
    Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production
    Xuan Du, Zhenlin Yang, Alfredo Jose Florez Ariza, Qian Wang, Guohui Xie, Sisi Li, Jiamu Du
    *Plant Cell*

2021

  • πŸ“„
    Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex
    Xiawei Huang, Hongmiao Hu, Alexandre Webster, Fan Zou, Jiamu Du, Dinshaw J Patel, Ravi Sachidanandam, Katalin Fejes Toth, Alexei A Aravin, Sisi Li
    *Nat. Commun.*
  • πŸ“„
    CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis
    Yifeng Hou, Jing Sun, Baixing Wu, Yangyang Gao, Hongbo Nie, Zhentian Nie, Shuxuan Quan, Yong Wang, Xiaofeng Cao, Sisi Li
    *Mol. Plant*
  • πŸ“„
    Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation
    Qian Wang, Yan Xue, Laixing Zhang, Zhenhui Zhong, Suhua Feng, Changshi Wang, Lifan Xiao, Zhenlin Yang, C Jake Harris, Zhe Wu, Jixian Zhai, Maojun Yang, Sisi Li, Steven E Jacobsen, Jiamu Du
    *Science*
  • πŸ“„
    Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release
    Wanqiu Li, Linlin Wang, Bradley M Wierbowski, Mo Lu, Feitong Dong, Wenchen Liu, Sisi Li, Peiyi Wang, Adrian Salic, Xin Gong
    *Nat. Commun.*
  • πŸ“„
    Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex
    Sisi Li, Tian Xie, Peng Liu, Lei Wang, Xin Gong
    *Nat. Struct. Mol. Biol.*
  • πŸ“„
    TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis
    Hongmiao Hu, Shu Tian, Guohui Xie, Rui Liu, Nana Wang, Sisi Li, Yuehui He, Jiamu Du
    *PNAS*

2020

  • πŸ“„
    Drosophila YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs
    Fan Zou, Renjun Tu, Bo Duan, Zhenlin Yang, Zhaohua Ping, Xiaoqing Song, Shiyuan Chen, Andrew Price, Hua Li, Allison Scott, Anoja Perera, Sisi Li, Ting Xie
    *PNAS*
  • πŸ“„
    Dual recognition of H3K4me3 and DNA by the ISWI component ARID5 regulates the floral transition in Arabidopsis
    Lian-Mei Tan, Rui Liu, Bo-Wen Gu, Cui-Jun Zhang, Jinyan Luo, Jing Guo, Yuhua Wang, Lixian Chen, Xuan Du, Sisi Li
    *Plant Cell*

2019

  • πŸ“„
    Structure of Arabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications for N6-methyl-AMP recognition and processing
    Baixing Wu, Dong Zhang, Hongbo Nie, Senlin Shen, Yan Li, Sisi Li
    *RNA Biol.*
  • πŸ“„
    The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor
    Shuzhi Zheng, Hongmiao Hu, Huimin Ren, Zhenlin Yang, Qi Qiu, Weiwei Qi, Xinye Liu, Xiaomei Chen, Xiekui Cui, Sisi Li
    *Nat. Commun.*

2018

  • πŸ“„
    Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation
    Xueqin Li, C Jake Harris, Zhenhui Zhong, Wei Chen, Rui Liu, Bei Jia, Zonghua Wang, Sisi Li, Steven E Jacobsen, Jiamu Du
    *PNAS*
  • πŸ“„
    Structure of the Arabidopsis JMJ14-H3K4me3 complex provides insight into the substrate specificity of KDM5 subfamily histone demethylases
    Zhenlin Yang, Qi Qiu, Wei Chen, Bei Jia, Xiaomei Chen, Hongmiao Hu, Kaixuan He, Xian Deng, Sisi Li, W Andy Tao
    *Plant Cell*

2016

  • πŸ“„
    Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors
    Yung-Chia Ariel Chen, Evelyn Stuwe, Yicheng Luo, Maria Ninova, Adrien Le Thomas, Ekaterina Rozhavskaya, Sisi Li, Sivani Vempati, John D Laver, Dinshaw J Patel
    *Mol. Cell*
  • πŸ“„
    Drosha and Dicer: Slicers cut from the same cloth
    Sisi Li, Dinshaw J Patel
    *Cell Res.*
  • πŸ“„
    Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
    Sisi Li, Linda Yen, William A Pastor, Jonathan B Johnston, Jiamu Du, Colin J Shew, Wanlu Liu, Jamie Ho, Bryan Stender, Amander T Clark, Alma L Burlingame, Lucia Daxinger, Dinshaw J Patel, Steven E Jacobsen
    *PNAS*
  • πŸ“„
    Structural basis for the unique multivalent readout of unmodified H3 tail by Arabidopsis ORC1b BAH-PHD cassette
    Sisi Li, Zhenlin Yang, Xuan Du, Rui Liu, Alex W Wilkinson, Or Gozani, Steven E Jacobsen, Dinshaw J Patel, Jiamu Du
    *Structure*
  • πŸ“„
    Structure and function of the bacterial decapping enzyme NudC
    Katharina HΓΆfer, Sisi Li, Florian Abele, Jens Frindert, Jasmin Schlotthauer, Julia Grawenhoff, Jiamu Du, Dinshaw J Patel, Andres JΓ€schke
    *Nat. Chem. Biol.*
  • πŸ“„
    The effect of MicroRNA bantam on baculovirus AcMNPV infection in vitro and in vivo
    Xiaojie Shi, Zihan Ran, Sisi Li, Juan Yin, Jiang Zhong
    *Viruses*

2015

  • πŸ“„
    Aub and Ago3 are recruited to nuage through two mechanisms to form a ping-pong complex assembled by Krimper
    Alexandre Webster, Sisi Li, Junho K Hur, Malte Wachsmuth, Justin S Bois, Edward M Perkins, Dinshaw J Patel, Alexei A Aravin
    *Mol. Cell*
  • πŸ“„
    TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms
    Boseon Kim, Minju Ha, Luuk Loeff, Hyeshik Chang, Dhirendra K Simanshu, Sisi Li, Mohamed Fareh, Dinshaw J Patel, Chirlmin Joo, V Narry Kim
    *EMBO J.*

2014

  • πŸ“„
    Mechanism of DNA methylation-directed histone methylation by KRYPTONITE
    Jiamu Du, Lianna M Johnson, Martin Groth, Suhua Feng, Christopher J Hale, Sisi Li, Ajay A Vashisht, Javier Gallego-Bartolome, James A Wohlschlegel, Dinshaw J Patel
    *Mol. Cell*
  • πŸ“„
    Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
    Adrien Le Thomas, Evelyn Stuwe, Sisi Li, Jiamu Du, Georgi Marinov, Nikolay Rozhkov, Yung-Chia Ariel Chen, Yicheng Luo, Ravi Sachidanandam, Katalin Fejes Toth
    *Genes Dev.*

2013

  • πŸ“„
    Functional and structural characterization of DNMT2 from Spodoptera frugiperda
    Sisi Li, Jiamu Du, Hui Yang, Juan Yin, Jianping Ding, Jiang Zhong
    *J. Mol. Cell Biol.*
  • πŸ“„
    Identification and characterization of the Spodoptera Su (var) 3-9 histone H3K9 trimethyltransferase and its effect in AcMNPV infection
    Binbin Li, Sisi Li, Juan Yin, Jiang Zhong
    *PLoS One*