Sisi Kang | Sisi Li Lab

Research Description

Using structural biology approaches to elucidate viral proteins and mechanisms of virus-host interactions.

🎓 Bachelor’s Degree, Huazhong University of Science and Technology (2005-2010)
🎓 Master’s Degree, Huazhong University of Science and Technology (2010-2013)
🎓 PhD, Sun Yat-sen University (2017-2020)
💼 Postdoctoral Fellow, Sun Yat-sen University (2020-2023)

1. Kang, S. #*, Yang, M.#, He, S.#, Wang, Y., Chen, X., Chen, Y. Q., Hong, Z., Liu, J., Jiang, G., Chen, Q., Zhou, Z., Zhou, Z., Huang, Z., Huang, X., He, H., Zheng, W., Liao, H. X., Xiao, F., Shan, H., & Chen, S. (2021). A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation. Nature communications, 12(1),2697.
1. Kang, S.*, Yang, M., Hong, Z., Zhang, L., Huang, Z., Chen, X., He, S., Zhou, Z., Zhou, Z., Chen, Q., Yan, Y., Zhang, C., Shan, H., & Chen, S. (2020). Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites. Acta pharmaceutica Sinica. B, 10(7), 1228–1238.
1. Yang, M., He, S., Chen, X., Huang, Z., Zhou, Z., Zhou, Z., Chen, Q., Chen, S., & Kang, S*. (2021). Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences. Frontiers in chemistry, 8,624765.
1. Zhou, Z., Kang, S*., Huang, Z., Zhou, Z., & Chen, S. (2021). Structural characteristics of coiled-coil regions in AF10-DOT1L and AF10-inhibitory peptide complex. Journal of leukocyte biology, 110(6), 1091–1099.
1. Kang, S.*, Wang, Z., Li, B., Gao, X., He, W., Cao, S., Cai, Y., & Chen, H. (2019). Anti-tumor effects of resveratrol on malignant melanoma is associated with promoter demethylation of RUNX3 gene. Die Pharmazie, 74(3), 163–167.